SymSitive* is a soothing ingredient for sensitive skin. With its neurosensory activity, SymSitive* provides instant and long-lasting relief from stinging, burning, and itching. Skin discomfort like tingling, burning and itching is characterized by a hyperresponsiveness of sensory neurons and stimulation of the thermoreceptor TRPV1 (capsaicin receptor). 

The Nobel Prize in Physiology and Medicine 2021 was awarded to David Julius and Ardem Patapoutian for the discovery of temperature receptor such as TRPV1.

SymSitive* acts on the Nobel Prize awarded mode of action of TRPV1 actively soothes the feeling of tingling, itching and burning.

*registered trademark of Symrise, Germany

Licochalcone A is a potent anti-inflammatory and antioxidant ingredient derived from the roots of the Chinese licorice plant (Glycyrrhiza inflata). Licochalcone A protects skin cells from oxidative stress and environmental aggressors like UV and blue light (HEVIS). Key benefits are:

• Antioxidant Defense: Activates antioxidant and detoxifying enzymes, shielding skin cells from oxidative damage, including lipid peroxidation, DNA- and protein damage.
• Anti-Inflammatory Action: Effectively reduces redness and soothes irritated skin, making it ideal for sensitive and irritated and stressed skin conditions.

Ceramides are essential skin lipids that form a key component of the epidermal barrier. They provide two main benefits:

• Barrier Function: Ceramides strengthen and restore the skin’s protective barrier, preventing transepidermal water loss and shielding against environmental stressors.
• Dry Skin Relief: By maintaining optimal hydration levels, ceramides alleviate symptoms of dryness, keeping the skin soft and resilient.

SymSitive* is a soothing ingredient for sensitive skin. With its neurosensory activity, SymSitive* provides instant and long-lasting relief from stinging, burning, and itching. Skin discomfort like tingling, burning and itching is characterized by a hyperresponsiveness of sensory neurons and stimulation of the thermoreceptor TRPV1 (capsaicin receptor). 

The Nobel Prize in Physiology and Medicine 2021 was awarded to David Julius and Ardem Patapoutian for the discovery of temperature receptor such as TRPV1.

SymSitive* acts on the Nobel Prize awarded mode of action of TRPV1 actively soothes the feeling of tingling, itching and burning.

*registered trademark of Symrise, Germany

Licochalcone A is a potent anti-inflammatory and antioxidant ingredient derived from the roots of the Chinese licorice plant (Glycyrrhiza inflata). Licochalcone A protects skin cells from oxidative stress and environmental aggressors like UV and blue light (HEVIS). Key benefits are:

• Antioxidant Defense: Activates antioxidant and detoxifying enzymes, shielding skin cells from oxidative damage, including lipid peroxidation, DNA- and protein damage.
• Anti-Inflammatory Action: Effectively reduces redness and soothes irritated skin, making it ideal for sensitive and irritated and stressed skin conditions.

Ceramides are essential skin lipids that form a key component of the epidermal barrier. They provide two main benefits:

• Barrier Function: Ceramides strengthen and restore the skin’s protective barrier, preventing transepidermal water loss and shielding against environmental stressors.
• Dry Skin Relief: By maintaining optimal hydration levels, ceramides alleviate symptoms of dryness, keeping the skin soft and resilient.